Cpg 7909 patent
WebAug 1, 2004 · For example, CpG 7909 (PF-3512676 or ODN2006), a 24-mer-B-Class CpG ODN and known TLR9 agonists, can induce the production of TNF-α and stimulate and … WebCpG ODN佐剂为一类已知具有佐剂特性的免疫刺激性寡聚核苷酸，能激活B细胞、NK、DC树突状等细胞，诱导释放IL-12、IFN-γ，从而诱导强Th1型应答和细胞免疫。 该种佐剂也是本领域技术人员所熟知的，已经在现有技术，例如国际申请已经在例如WO 96/02555、WO 99/33488中描述过。 目前已有一些商业化的CpG ODN佐剂，例如CpG 7909...
Cpg 7909 patent
Did you know?
WebJan 14, 2024 · Alternative Names: Agatolimod sodium; CpG 7909; CPG ODN 2006; CpG oligodeoxynucleotide 7909; PF-3512676; PF-676; ProMune Latest Information Update: … Web调节免疫反应的核酸成分专利检索，调节免疫反应的核酸成分属于·碳水化合物糖其衍生物专利检索，找专利汇即可免费查询专利，·碳水化合物糖其衍生物专利汇是一家知识产权数据服务商，提供专利分析，专利查询，专利检索等数据服务功能。
WebCpG 7909, acting through the TLR9 receptor present in B cells and plasmacytoid dendritic cells, stimulates human B-cell proliferation, enhances antigen-specific antibody production and induces interferon-alpha production, interleukin-10 … WebOct 23, 2012 · Three US patents relating to CpG 7909 and the use of certain oligonucleotides for treating cancer are due to expire in 2014. Coley also has pending US …
WebLGM Pharma is a US-based CpG ODN 7909 API supplier distributor. Ask about DMF, price & availability. See product details. ... Products currently covered by valid US Patents are … WebAug 12, 2002 · CPG 7909 Plus Herceptin® In Patients With Metastatic Breast Cancer The safety and scientific validity of this study is the responsibility of the study sponsor and …
WebApr 15, 2008 · CPG 7909 is an oligodeoxynucleotide containing immunostimulatory CpG motifs that activate human B and plasmacytoid dendritic cells via Toll-like receptor 9. We previously reported that addition of CPG 7909 to a commercial HBV vaccine enhanced the kinetics, magnitude, and longevity of the seroprotective response over 48 weeks.
WebNov 1, 2003 · CpG-7909 (TCGTCGTTTTGTCGTTTTGTC-GTT; phosphorothioate backbone) (28) ... The aim of this article is to review most significant patents on immunostimulatory oligonucleotides. View. black decker dcm2500b smartbrew coffeemakerWebSep 23, 2005 · We evaluated CPG 7909, a synthetic oligodeoxynucleotide containing immunostimulatory CpG motifs, as an adjuvant to Engerix-B. A randomized, double-blind controlled trial was conducted to determine safety and hepatitis B virus (HBV) immunogenicity in adult HIV subjects on effective antiretroviral therapy. gambler\u0027s help southernWebCpG 7909 [PF-3512676] is an immunomodulating synthetic oligonucleotide designed to specifically agonise the Toll-like receptor 9 (TLR9). It is being developed for the … gambler\u0027s fallacy law and order svuWebSynthetic oligodeoxynucleotides (ODNs) containing unmethylated CpG motifs trigger cells that express Toll-like receptor 9 (including human plasmacytoid dendritic cells and B … black decker direct parts productsWebAug 12, 2002 · Experimental: CPG 7909 Injection. Drug: CPG 7909. In the phase I portion of the protocol, patients will be included in escalating dose groups: 0.08, 0.12, 0.16, 0.36, 0.54 or 0.81 mg/kg of CPG 7909 Injection. Patients will be treated once weekly subcutaneously for 24 weeks. In the Phase II portion of the trial patients will be treated at the ... black decker cultivator cordlessWebMar 1, 2002 · Brief Summary: The purpose of this study is to determine if the combination of CPG 7909 and Herceptin is safe and effective in the treatment of metastatic breast … gambler\u0027s lifeWebThe present disclosure further provides a method of inducing an immunological response against an influenza virus in a subject in need thereof, comprising administering a dose of about 20 μg to about 300 μg of an HA-ss-np in a vaccine composition, wherein the vaccine composition further comprises an aluminum hydroxide; CpG ODN; and a ... blackdecker double flip waffle maker